If you are sensitive to allergen such as ragweed pollen or chemical such as paint, once contacted it will precipitate your immune system into releasing histamines from the mast cells and attaches to the receptors in the surrounding blood vessels causing them to enlarge. Histamine will also bind to other receptors, which causes redness, swelling and itching. Antihistamines prevent these symptoms from occurring by blocking these histamine receptors.
There are four kinds of histamine receptors, H1, H2, H3 and H4. They are all G protein-coupled receptors, of which the H1 receptor is the only one when histamine binds to it will cause allergic reaction that leads to hives rash. H1 receptor antagonists (Antihistamine) such as Diphenhydramine, Loratadine, Cetirizine, Fexofenadine blocks off histamine from binding to the H1 receptor which causes hives rash with symptoms like itching and swelling of the skin.
Most symptoms of hives rash respond very well to antihistamine. there are many forms of antihistamines available. They include fast-acting and long-acting forms and are available as tablets, nasal-inhalers, eye drops, and syrups.
Examples of Over-The-Counter Antihistamine are Allegra, Benadryl, Claritin, Chlor-Trimeton, Dimetane, Zyrtec, and Tavist.
Examples of Prescription Antihistamines are Clarinex and Xyzal, Promethazine, Tussionex, Tylenol, Astelin, Emadine and Liyostin.
*Astelin is a prescription nasal spray and Emadine and Livostin are eye drops.
Hives Treatment Overview
There is no cure for hives rash, as evident by the lack of solid evidence that causes it. The commonly used antihistamines medication is only a symptom treatment that is effective in suppressing the histamine effects, but does not prevent recurrence. Though in most people who suffers from hives rash, the problem usually last for a few days and subside, even without any medication. But that few days will seem like years with all that discomfort of skin swelling, burning and itching.
What about people suffering from chronic hives? If you know of someone or even yourself who had been through that experience, you know how desperate and hapless it can be. it is both physical and mental stress to the max.
So what is the most effective hives treatment that will last forever?
Primarily, hives rash is an indication of a weak immune system. The best cure is still prevention. Boost up your immune system and avoid contact with those allergens that you are allergic to, then you are less likely to face another hives attack. But as mentioned before, the causes of hives are very elusive, the factors are wide ranging and unpredictable. In any case, if you are face with hives rash, there are always treatments at bay to help alleviate the discomfort.
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